const regex = /\.\d+(*SKIP)(*FAIL)|\B(?=(?:\d{3})+(?!\d))/gm;
// Alternative syntax using RegExp constructor
// const regex = new RegExp('\\.\\d+(*SKIP)(*FAIL)|\\B(?=(?:\\d{3})+(?!\\d))', 'gm')
const str = `123456789.1
123456789
1.1
10.1
100.1
1000.1
10000.11
100000.1111111111
1000000.111
10000000.11111.1111
100000000.111111
1000000000.1111111
123456789
1
10
100
1000
10000
100000
1000000
10000000
100000000
1000000000`;
const subst = `,`;
// The substituted value will be contained in the result variable
const result = str.replace(regex, subst);
console.log('Substitution result: ', result);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for JavaScript, please visit: https://developer.mozilla.org/en/docs/Web/JavaScript/Guide/Regular_Expressions