#include <MsgBoxConstants.au3> ; to declare the Constants of MsgBox
Local $sRegex = "(?m)(/\*\s*ABCD[^*/]*)\*/\s*/\*\s*Comment[^*:]+:(\s*\[\[[^][]*]]\s*\*/)"
Local $sString = "/* ABCD X 1111 */ /* Comment 1111: [[reason for comment]] */"
Local $sSubst = "\1#\2"
Local $sResult = StringRegExpReplace($sString, $sRegex, $sSubst)
MsgBox($MB_SYSTEMMODAL, "Result", $sResult)
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for AutoIt, please visit: https://www.autoitscript.com/autoit3/docs/functions/StringRegExp.htm