re = /^.*?(?=\d*[a-z]\d*[a-z]|$)/mi
str = '1234 123423-34 b4 3-z a 234 This is a test
1234 123423-34 b4 3-z a 234This is a test
1234 123423-34 b4 3-z a '
subst = ''
result = str.gsub(re, subst)
# Print the result of the substitution
puts result
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Ruby, please visit: http://ruby-doc.org/core-2.2.0/Regexp.html