$re = '/,?(-?\d+(?:[.,]\d+)?)(?=.*\1)/m';
$str = '0,0,67,67,0
-30,-30
1.46,1.46
67,67,67,67,67,67,0,0,0,0,0,0,67,67,67,67,67,67';
$subst = "";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php