$re = '`^(?:(?:(?:Miss|Mr|Lady|Mrs|Ms|Dr|Sir)\b|Mr\.)\s+)?(\S+)`m';
$str = 'Mrs Daksha Karsan
Mr Shane Kyle Taylor
Mr Ahmed Demerdash Keyani
Perry Joe Wilson
Miss Chantelle Reece
Mike Stewart
Dr Ariel Verun Patel
Mr John Sim
';
$subst = "$1";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php