# If you'd like to omit non-matching lines from the result; add ';d' to the end of the expression.
sed -E 's/<a[^>]*>.*?<\/a\s*>(*SKIP)(*FAIL)|\borlistat\b/<a href="ddd">orlistat<\/a>/s;t' <<< "
<li><a href=\"/Dimagrire/Farmaci/orlistat.html\"><strong>Orlistat</strong></a>, inibitore delle lipasi gastroenteriche, in grado di ridurre orlistat sensibilmente l'assorbimento intestinale dei grassi alimentari, tagliando così il potere calorico della dieta. <br />
"
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for SED, please visit: https://www.gnu.org/software/sed/manual/html_node/The-_0022s_0022-Command.html