use strict;
my $str = '<et>A rpg</et>
<et>B rpg</et>
<et>C rpg</et>
<et>D rpg</et>
<et>E rpg</et>
<et>F rpg</et>';
my $regex = qr/(<et>.*)\brpg\b/p;
my $subst = '$1rts';
my $result = $str =~ s/$regex/$subst/rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html