$re = '/^(.+)(\' \+[\r\n]{1,2} +\')(.+)$/';
$str = ' \'where v.VagonID=:VagonID and v.Vypis_ID is null and v.Nat_List_I\' +
\'D is null and v.Block<>1\')';
$subst = "\1\3";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php