re = /\w(?=\w{4})/m
str = '4f563a46jy7u35616
4f56sdfsddf
okmefiwmkiol
drejkskmilw
123434355454
34223'
subst = '#'
result = str.gsub(re, subst)
# Print the result of the substitution
puts result
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Ruby, please visit: http://ruby-doc.org/core-2.2.0/Regexp.html