#include <MsgBoxConstants.au3> ; to declare the Constants of MsgBox
Local $sRegex = "(?<=\d),(?=\d)"
Local $sString = "00:00:00,166 --> 00:00:03,999 In this section we will look at"
Local $sSubst = "."
Local $sResult = StringRegExpReplace($sString, $sRegex, $sSubst)
MsgBox($MB_SYSTEMMODAL, "Result", $sResult)
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for AutoIt, please visit: https://www.autoitscript.com/autoit3/docs/functions/StringRegExp.htm