$re = '/(?<!\w)\d+(?<!\")/ms';
$str = '
"gnhgnghb grhgf ytjy 4444 rewgefgg gfbvc" 234234 =2345234
sdhjaklf382as;ldfj asda2334= 76555
=123123
:1233
"gnhgnghb grhgf ytjy4444 rewgefgg
gfbvc"
"gnhgnghb grhgf ytjy 4444 rewgefgg
gfbvc"';
$subst = "";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php