$re = '/(\d+:\d+)(\s+[^<]+?)<br>/m';
$str = '1:10 - some text<br>';
$subst = "<span class=\"time\">$1</span>$2<br>";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php