$re = '/^(.*)[.]([0-9]{1})(b|B)([0-9]{1,2})[.](.*)$/m';
$str = 'abcd.1B21.efg.hi.txt
abcd.1b21.efg.h2i.txt
';
$subst = "$1.0$2b$4$5";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php