use strict;
my $str = 'homo_seg-Val-abc-1-1
homo_seg-Beg-cdf-2-1
homo_seg-Try-gfh-3-2
homo_seg-Fuss-cdh-3-1';
my $regex = qr/homo_seg-/mp;
my $subst = '';
my $result = $str =~ s/$regex/$subst/rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html