re = /^(?!.*_en)(.*)$/m
str = 'value_1_en
value_1
value_2_en
value_2
value_3_en
value_3'
subst = '\\1_fr'
result = str.gsub(re, subst)
# Print the result of the substitution
puts result
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Ruby, please visit: http://ruby-doc.org/core-2.2.0/Regexp.html