$re = '/^(<[^<>]*>;\srel=\"(next|prev|last|first)\"(,\s)?)*$/';
$str = '<https://api.github.com/user/25254/followers?page=21>; rel="next", <https://api.github.com/user/25254/followers?page=332>; rel="last", <https://api.github.com/user/25254/followers?page=1>; rel="first", <https://api.github.com/user/25254/followers?page=19>; rel="prev"';
preg_match($re, $str, $matches, PREG_OFFSET_CAPTURE, 0);
// Print the entire match result
var_dump($matches);
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php