use strict;
my $str = 'something here<!---->
<!--[if IE 6]>
Special instructions for IE 6 here
<![endif]-->
something here<!-- -->
<!--[if lt IE 9]> <!-- -->
Here is some code.
<![endif]-->
<!--[if !IE]> -->
<![endif]-->';
my $regex = qr/<!--([^<|\s|\[|>|go{2}gleo]).*?-->/mp;
my $subst = '';
my $result = $str =~ s/$regex/$subst/rg;
print "The result of the substitution is' $result\n";
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for Perl, please visit: http://perldoc.perl.org/perlre.html