$re = '/<!--([^<|\s|\[|>|go{2}gleo]).*?-->/m';
$str = 'something here<!---->
<!--[if IE 6]>
Special instructions for IE 6 here
<![endif]-->
something here<!-- -->
<!--[if lt IE 9]> <!-- -->
Here is some code.
<![endif]-->
<!--[if !IE]> -->
<![endif]-->';
$subst = "";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php