$re = '~://[^.:]+~';
$str = 'http://localhost:8080/test
-> http://{HOST_NAME}:8080/test
https://test-app.uk.ru/test
-> https://{HOST_NAME}.uk.ru/test';
$subst = "://{HOST_NAME}";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php