$re = '/(.*?)__P\((.*?)\);/s';
$str = 'char *x __P((char *, size_t,
void *, size_t, int));
char *y __P((void *, const char *, int));';
$subst = "\1\2;";
$result = preg_replace($re, $subst, $str);
echo "The result of the substitution is ".$result;
Please keep in mind that these code samples are automatically generated and are not guaranteed to work. If you find any syntax errors, feel free to submit a bug report. For a full regex reference for PHP, please visit: http://php.net/manual/en/ref.pcre.php